ASCVD is a progressive disease characterized by the accumulation of plaques in arterial walls, causing blood vessels to narrow or block. This limits blood flow, increasing the risk of heart attacks, strokes, and other cardiovascular events. The formation of plaques begins early in life, often promoted by inflammation, oxidative stress, and high levels of lipoproteins containing apoB.
Certain medical habits and conditions increase the risk of heart failure.
Excess weight puts a strain on the heart and worsens other risk factors.
Increases the risk of weakening the heart muscle.
Damages blood vessels and increases cardiac workload.
Expresses additional pressure on the heart over time
ASCVD often remains asymptomatic until significant arterial narrowing or blockage occurs, leading to acute cardiovascular events.
Discomfort caused by reduced blood flow to the heart.
Indicates a decrease in oxygen supply due to restricted blood flow.
Pain or cramps in the legs during activity due to the involvement of peripheral arteries.
Pain or cramps in the legs during activity due to the involvement of peripheral arteries.
Early detection relies on advanced imaging and biomarker testing to assess arterial health and identify risks.
Measures the number of atherogenic lipoproteins.
Ideal score
<60 mg/dL.
High risk
>130 mg/dL
Quantifies the calcification of the coronary arteries.
Ideal score<60 mg/dL.
High risk
>300 mg/dL
Assess hereditary risk.
Ideal score
<50 mg/dL
High risk
>100 mg/dL
Detect hyperinsulinemia.
Ideal score<5 μIU/ml
High risk
>20 μIU/ml
ASCVD treatment combines lifestyle interventions, medications, and in severe cases, procedural options to restore blood flow.