Parkinson's disease is a progressive neurodegenerative disorder primarily affecting motor control due to the loss of dopamine-producing neurons in the brain. It is manifested by tremors, stiffness, bradykinesia (impairment of movements) and postural instability. Although the exact cause remains unknown, genetic and environmental factors contribute significantly. Lifestyle changes and emerging therapies aim to slow the progression of the disease.
Lifestyle factors, while not primary causes, influence the onset and progression of Parkinson's disease.
Lack of movement can reduce resilience in the face of motor degeneration.
Pesticides, herbicides, and heavy metals have been associated with increased risk.
Associated with a decrease in glucose metabolism in the brain and an increased risk of neurodegeneration.
Diets low in antioxidants may exacerbate oxidative stress in neurons.
The symptoms of Parkinson's disease progress, affecting motor and non-motor functions.
There are no definitive tests for Parkinson's disease; diagnosis is based on clinical evaluations and imaging.
The diagnosis is based on the observation of motor symptoms and the response to dopamine therapy.
Assess dopamine transporter levels in the brain
Identify mutations in genes such as LRRK2 or SNCA associated with familial Parkinson's disease.
Therapeutic interventions focus on managing symptoms and improving quality of life.
Exercises to improve balance, strength, and flexibility.
Surgical implantation of electrodes to modulate brain activity in advanced cases.
Surgical implantation of electrodes to modulate brain activity in advanced cases.
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