Prediabetes is a metabolic condition where blood sugar levels are high, but not yet high enough to qualify as type 2 diabetes (T2D). It is an early sign of insulin resistance, often reversible through lifestyle changes. Without intervention, prediabetes can develop into proven T2D and increase the risk of cardiovascular disease, cancer, and neurodegenerative disorders.
Lifestyle and metabolic factors contribute significantly to the development of prediabetes.
A diet high in refined carbohydrates and sugars exacerbates insulin resistance.
The accumulation of visceral fat in particular increases metabolic dysfunctions.
Sedentary behavior reduces glucose uptake by muscles.
Poor sleep quality elevates cortisol, which disrupts glucose regulation.
Prolonged stress triggers hormonal imbalances that affect metabolism.
Prediabetes is often asymptomatic, making regular screening essential.
A sign of glucose misuse.
Appears in the neck, armpits or groin as a marker of insulin resistance.
Subtle signs of a possible increase in blood sugar levels.
Advances in imaging and biomarker testing allow for earlier and more accurate detection of Alzheimer's disease.
Normal
<60 mg/dL.
Prediabetic
100—125 mg/dL
Reflects the average blood sugar level over three months.
Normal
< 5.7%
Prediabetic
5.7% - 6.4%
High glucose levels two hours after ingestion of 75 g of glucose indicate insulin resistance.
Reversing insulin resistance requires regular exercise and a low-carb diet to improve glucose uptake, reduce metabolic stress, and extend longevity.
Regular aerobic activity at moderate intensity helps improve mitochondrial health, glucose uptake, and overall metabolic flexibility.
A reduction in calorie intake can decrease insulin resistance and metabolic dysfunction.
A Mediterranean or ketogenic diet can help lower insulin levels and improve glucose metabolism. Reducing refined carbohydrates, added sugars, and alcohol is recommended.